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Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology

Over 20 years ago, sphingosine-1-phosphate (S1P) was discovered to be a bioactive signaling molecule. Subsequent studies later identified two related kinases, sphingosine kinase 1 and 2, which are responsible for the phosphorylation of sphingosine to S1P. Many stimuli increase sphingosine kinase act...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Rohrbach, Timothy, Maceyka, Michael, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944845/
https://ncbi.nlm.nih.gov/pubmed/28618839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2017.1337706
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