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Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond
The bioactive lipid sphingosine-1-phosphate (S1P) is involved in multiple cellular signalling systems and has a pivotal role in the control of immune cell trafficking. As such, S1P has been implicated in disorders such as cancer and inflammatory diseases. This Review discusses the ways in which S1P...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908769/ https://ncbi.nlm.nih.gov/pubmed/23954895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4099 |
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