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SPHINGOSINE-1-PHOSPHATE SIGNALING AND ITS ROLE IN DISEASE
The bioactive sphingolipid metabolite, sphingosine-1-phosphate (S1P), is now recognized as a critical regulator of many physiological and pathophysiological processes, including cancer, atherosclerosis, diabetes and osteoporosis. S1P is produced in cells by two sphingosine kinase isoenzymes, SphK1 a...
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| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253987/ https://ncbi.nlm.nih.gov/pubmed/22001186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2011.09.003 |
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