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DEVELOPMENT OF SMALL-MOLECULE INHIBITORS OF SPHINGOSINE-1-PHOSPHATE SIGNALING

The pleiotropic sphingolipid mediator, sphingosine-1-phosphate, produced in cells by two sphingosine kinase isoenzymes, SphK1 and SphK2, regulates many cellular and physiological processes important for homeostasis and development and pathophysiology. Many of the actions of S1P are mediated by a fam...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Edmonds, Yvette, Milstien, Sheldon, Spiegel, Sarah
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205210/
https://ncbi.nlm.nih.gov/pubmed/21906625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2011.08.004
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