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Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling

The sphingolipid metabolite sphingosine-1-phosphate (S1P) and the kinases that produce it have emerged as critical regulators of numerous fundamental biological processes important for health and disease. Activation of sphingosine kinases (SphKs) by a variety of agonists increases intracellular S1P,...

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Detalhes bibliográficos
Main Authors: Maceyka, Michael, Milstien, Sheldon, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674705/
https://ncbi.nlm.nih.gov/pubmed/18987387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800065-JLR200
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