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Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biological processes by binding to a family of G protein–coupled receptors or as an intracellular second messenger. Mammalian S1P phosphatase (SPP-1), which degrades S1P to terminate its actions, was recently...

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Detalhes bibliográficos
Main Authors: Le Stunff, Hervé, Galve-Roperh, Ismael, Peterson, Courtney, Milstien, Sheldon, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173216/
https://ncbi.nlm.nih.gov/pubmed/12235122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203123
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