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Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology
Over 20 years ago, sphingosine-1-phosphate (S1P) was discovered to be a bioactive signaling molecule. Subsequent studies later identified two related kinases, sphingosine kinase 1 and 2, which are responsible for the phosphorylation of sphingosine to S1P. Many stimuli increase sphingosine kinase act...
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| Published in: | Crit Rev Biochem Mol Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944845/ https://ncbi.nlm.nih.gov/pubmed/28618839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2017.1337706 |
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