Hallmarks of response to immune checkpoint blockade

由 Cogdill, Alexandria P, Andrews, Miles C, Wargo, Jennifer A
發表在 Br J Cancer (2017)

Gene targeting meets cell-based therapy: raising the tail, or merely a whimper?

由 Cogdill, Alexandria P., Prieto, Peter A., Reuben, Alexandre, Wargo, Jennifer A.
發表在 Clin Cancer Res (2016)

Potential role of 5- aza-2’-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer

由 Gunda, Viswanath, Cogdill, Alexandria P., Bernasconi, Maria J., Wargo, Jennifer A., Parangi, Sareh
出版 2013

Targeting the MAGE A3 antigen in pancreatic cancer

由 Cogdill, Alexandria P., Frederick, Dennie T., Cooper, Zachary A., Garber, Haven R., Ferrone, Cristina R., Fiedler, Amy, Rosenberg, Laura, Thayer, Sarah P., Warshaw, Andrew L., Wargo, Jennifer A.
出版 2012

Distinct cellular mechanisms underlie anti-CTLA-4 and anti-PD-1 checkpoint blockade

由 Wei, Spencer C., Levine, Jacob H., Cogdill, Alexandria P., Zhao, Yang, Anang, Nana-Ama A.S., Andrews, Miles C., Sharma, Padmanee, Wang, Jing, Wargo, Jennifer A., Pe'er, Dana, Allison, James P.
發表在 Cell (2017)

Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies

由 Wei, Spencer C., Anang, Nana-Ama A. S., Sharma, Roshan, Andrews, Miles C., Reuben, Alexandre, Levine, Jacob H., Cogdill, Alexandria P., Mancuso, James J., Wargo, Jennifer A., Pe’er, Dana, Allison, James P.
發表在 Proc Natl Acad Sci U S A (2019)

Affinity-tuned ErbB2 or EGFR chimeric antigen receptor T cells exhibit an increased therapeutic index against tumors in mice

由 Liu, Xiaojun, Jiang, Shuguang, Fang, Chongyun, Yang, Shiyu, Olalere, Devvora, Pequignot, Edward C., Cogdill, Alexandria P., Li, Na, Ramones, Melissa, Granda, Brian, Zhou, Li, Loew, Andreas, Young, Regina M., June, Carl H., Zhao, Yangbing
發表在 Cancer Res (2015)

EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib

由 Corcoran, Ryan B., Ebi, Hiromichi, Turke, Alexa B., Coffee, Erin M., Nishino, Michiya, Cogdill, Alexandria P., Brown, Ronald D., Pelle, Patricia Della, Dias-Santagata, Dora, Hung, Kenneth E., Flaherty, Keith T., Piris, Adriano, Wargo, Jennifer A., Settleman, Jeffrey, Mino-Kenudson, Mari, Engelman, Jeffrey A.
出版 2012

BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma

由 Frederick, Dennie Tompers, Piris, Adriano, Cogdill, Alexandria P., Cooper, Zachary A., Lezcano, Cecilia, Ferrone, Cristina R., Mitra, Devarati, Boni, Andrea, Newton, Lindsay P., Liu, Chengwen, Peng, Weiyi, Sullivan, Ryan J, Lawrence, Donald P., Hodi, F. Stephen, Overwijk, Willem W., Lizée, Gregory, Murphy, George F., Hwu, Patrick, Flaherty, Keith T., Fisher, David E., Wargo, Jennifer A.
出版 2013

Pre-clinical validation of a humanized anti-EGFR variant III chimeric antigen receptor and phase I trial of CART-EGFRvIII in glioblastoma

由 Johnson, Laura A, Scholler, John, Ohkuri, Takayuki, Kosaka, Akemi, Patel, Prachi R, McGettigan, Shannon E, Nace, Arben, Thekkat, Pramod, Loew, Andreas, Chen, Taylor J, Fraietta, Joseph A, Posey, Avery D, Boesteanu, Alina C, Cogdill, Alexandria P, Engels, Boris, Singh, Reshma, Ezell, Tucker R, Idamakanti, Neeraja, Plesa, Gabriela, Seykora, John, Okada, Hideho, June, Carl, Brogdon, Jennifer, Maus, Marcela
發表在 J Immunother Cancer (2014)

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

由 Posey, Avery D., Schwab, Robert D., Boesteanu, Alina C., Steentoft, Catharina, Mandel, Ulla, Engels, Boris, Stone, Jennifer D., Madsen, Thomas D., Schreiber, Karin, Haines, Kathleen M., Cogdill, Alexandria P., Chen, Taylor J., Song, Decheng, Scholler, John, Kranz, David M., Feldman, Michael D., Young, Regina, Keith, Brian, Schreiber, Hans, Clausen, Henrik, Johnson, Laura A., June, Carl H.
發表在 Immunity (2016)

Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas

由 Yin, Yibo, Boesteanu, Alina C., Binder, Zev A., Xu, Chong, Reid, Reiss A., Rodriguez, Jesse L., Cook, Danielle R., Thokala, Radhika, Blouch, Kristin, McGettigan-Croce, Bevin, Zhang, Logan, Konradt, Christoph, Cogdill, Alexandria P., Panjwani, M. Kazim, Jiang, Shuguang, Migliorini, Denis, Dahmane, Nadia, Posey, Avery D., June, Carl H., Mason, Nicola J., Lin, Zhiguo, O’Rourke, Donald M., Johnson, Laura A.
發表在 Mol Ther Oncolytics (2018)

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

由 Johnson, Laura A., Morgan, Richard A., Dudley, Mark E., Cassard, Lydie, Yang, James C., Hughes, Marybeth S., Kammula, Udai S., Royal, Richard E., Sherry, Richard M., Wunderlich, John R., Lee, Chyi-Chia R., Restifo, Nicholas P., Schwarz, Susan L., Cogdill, Alexandria P., Bishop, Rachel J., Kim, Hung, Brewer, Carmen C., Rudy, Susan F., VanWaes, Carter, Davis, Jeremy L., Mathur, Aarti, Ripley, Robert T., Nathan, Debbie A., Laurencot, Carolyn M., Rosenberg, Steven A.
出版 2009

Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma

由 Johnson, Laura A., Scholler, John, Ohkuri, Takayuki, Kosaka, Akemi, Patel, Prachi R., McGettigan, Shannon E., Nace, Arben K., Dentchev, Tzvete, Thekkat, Pramod, Loew, Andreas, Boesteanu, Alina C., Cogdill, Alexandria P., Chen, Taylor, Fraietta, Joseph A., Kloss, Christopher C., Posey, Avery D., Engels, Boris, Singh, Reshma, Ezell, Tucker, Idamakanti, Neeraja, Ramones, Melissa H., Li, Na, Zhou, Li, Plesa, Gabriela, Seykora, John T., Okada, Hideho, June, Carl H., Brogdon, Jennifer L., Maus, Marcela V.
發表在 Sci Transl Med (2015)

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

由 Fraietta, Joseph A., Beckwith, Kyle A., Patel, Prachi R., Ruella, Marco, Zheng, Zhaohui, Barrett, David M., Lacey, Simon F., Melenhorst, Jan Joseph, McGettigan, Shannon E., Cook, Danielle R., Zhang, Changfeng, Xu, Jun, Do, Priscilla, Hulitt, Jessica, Kudchodkar, Sagar B., Cogdill, Alexandria P., Gill, Saar, Porter, David L., Woyach, Jennifer A., Long, Meixiao, Johnson, Amy J., Maddocks, Kami, Muthusamy, Natarajan, Levine, Bruce L., June, Carl H., Byrd, John C., Maus, Marcela V.
發表在 Blood (2016)

COT/MAP3K8 drives resistance to RAF inhibition through MAP kinase pathway reactivation

由 Johannessen, Cory M., Boehm, Jesse S., Kim, So Young, Thomas, Sapana R., Wardwell, Leslie, Johnson, Laura A., Emery, Caroline M., Stransky, Nicolas, Cogdill, Alexandria P., Barretina, Jordi, Caponigro, Giordano, Hieronymus, Haley, Murray, Ryan R., Salehi-Ashtiani, Kourosh, Hill, David E., Vidal, Marc, Zhao, Jean J., Yang, Xiaoping, Alkan, Ozan, Kim, Sungjoon, Harris, Jennifer L., Wilson, Christopher J., Myer, Vic E., Finan, Peter M., Root, David E., Roberts, Thomas M., Golub, Todd, Flaherty, Keith T., Dummer, Reinhard, Weber, Barbara, Sellers, William R., Schlegel, Robert, Wargo, Jennifer A., Hahn, William C., Garraway, Levi A.
出版 2010

Disruption of TET2 Promotes the Therapeutic Efficacy of CD19-targeted T-cells

由 Fraietta, Joseph A., Nobles, Christopher L., Sammons, Morgan A., Lundh, Stefan, Carty, Shannon A., Reich, Tyler, Cogdill, Alexandria P., Morrissette, Jennifer J.D., DeNizio, Jamie E., Reddy, Shantan, Hwang, Young, Gohil, Mercy, Kulikovskaya, Irina, Nazimuddin, Farzana, Gupta, Minnal, Chen, Fang, Everett, John K., Alexander, Katherine A., Lin-Shiao, Enrique, Gee, Marvin H., Liu, Xiaojun, Young, Regina M., Ambrose, David, Wang, Yan, Xu, Jun, Jordan, Martha S., Marcucci, Katherine T., Levine, Bruce L., Garcia, K. Christopher, Zhao, Yangbing, Kalos, Michael, Porter, David L., Kohli, Rahul M., Lacey, Simon F., Berger, Shelley L., Bushman, Frederic D., June, Carl H., Melenhorst, J. Joseph
發表在 Nature (2018)

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma

由 Reuben, Alexandre, Spencer, Christine N., Prieto, Peter A., Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Miller, John P., Mao, Xizeng, De Macedo, Mariana Petaccia, Chen, Jiong, Song, Xingzhi, Jiang, Hong, Chen, Pei-Ling, Beird, Hannah C., Garber, Haven R., Roh, Whijae, Wani, Khalida, Chen, Eveline, Haymaker, Cara, Forget, Marie-Andrée, Little, Latasha D., Gumbs, Curtis, Thornton, Rebecca L., Hudgens, Courtney W., Chen, Wei-Shen, Austin-Breneman, Jacob, Sloane, Robert Szczepaniak, Nezi, Luigi, Cogdill, Alexandria P., Bernatchez, Chantale, Roszik, Jason, Hwu, Patrick, Woodman, Scott E., Chin, Lynda, Tawbi, Hussein, Davies, Michael A., Gershenwald, Jeffrey E., Amaria, Rodabe N., Glitza, Isabella C., Diab, Adi, Patel, Sapna P., Hu, Jianhua, Lee, Jeffrey E., Grimm, Elizabeth A., Tetzlaff, Michael T., Lazar, Alexander J., Wistuba, Ignacio I., Clise-Dwyer, Karen, Carter, Brett W., Zhang, Jianhua, Futreal, P. Andrew, Sharma, Padmanee, Allison, James P., Cooper, Zachary A., Wargo, Jennifer A.
發表在 NPJ Genom Med (2017)

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

由 Nejman, Deborah, Livyatan, Ilana, Fuks, Garold, Gavert, Nancy, Zwang, Yaara, Geller, Leore T, Rotter-Maskowitz, Aviva, Weiser, Roi, Mallel, Giuseppe, Gigi, Elinor, Meltser, Arnon, Douglas, Gavin M, Kamer, Iris, Gopalakrishnan, Vancheswaran, Dadosh, Tali, Levin-Zaidman, Smadar, Avnet, Sofia, Atlan, Tehila, Cooper, Zachary A, Arora, Reetakshi, Cogdill, Alexandria P, Khan, Md Abdul Wadud, Ologun, Gabriel, Bussi, Yuval, Weinberger, Adina, Lotan-Pompan, Maya, Golani, Ofra, Perry, Gili, Rokah, Merav, Bahar-Shany, Keren, Rozeman, Elisa A, Blank, Christian U, Ronai, Anat, Shaoul, Ron, Amit, Amnon, Dorfman, Tatiana, Kremer, Ran, Cohen, Zvi R, Harnof, Sagi, Siegal, Tali, Yehuda-Shnaidman, Einav, Gal-Yam, Einav Nili, Shapira, Hagit, Baldini, Nicola, Langille, Morgan G I, Ben-Nun, Alon, Kaufman, Bella, Nissan, Aviram, Golan, Talia, Dadiani, Maya, Levanon, Keren, Bar, Jair, Yust-Katz, Shlomit, Barshack, Iris, Peeper, Daniel S, Raz, Dan J, Segal, Eran, Wargo, Jennifer A, Sandbank, Judith, Shental, Noam, Straussman, Ravid
發表在 Science (2020)