BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma

PURPOSE: To evaluate the effects BRAF inhibition on the tumor microenvironment in patients with metastatic melanoma. EXPERIMENTAL DESIGN: Thirty-five biopsies were collected from 16 patients with metastatic melanoma pretreatment (day 0) and at 10-14 days after initiation of treatment with either BRA...

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Main Authors: Frederick, Dennie Tompers, Piris, Adriano, Cogdill, Alexandria P., Cooper, Zachary A., Lezcano, Cecilia, Ferrone, Cristina R., Mitra, Devarati, Boni, Andrea, Newton, Lindsay P., Liu, Chengwen, Peng, Weiyi, Sullivan, Ryan J, Lawrence, Donald P., Hodi, F. Stephen, Overwijk, Willem W., Lizée, Gregory, Murphy, George F., Hwu, Patrick, Flaherty, Keith T., Fisher, David E., Wargo, Jennifer A.
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752683/
https://ncbi.nlm.nih.gov/pubmed/23307859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1630
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