BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma

PURPOSE: To evaluate the effects BRAF inhibition on the tumor microenvironment in patients with metastatic melanoma. EXPERIMENTAL DESIGN: Thirty-five biopsies were collected from 16 patients with metastatic melanoma pretreatment (day 0) and at 10-14 days after initiation of treatment with either BRA...

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Hlavní autoři: Frederick, Dennie Tompers, Piris, Adriano, Cogdill, Alexandria P., Cooper, Zachary A., Lezcano, Cecilia, Ferrone, Cristina R., Mitra, Devarati, Boni, Andrea, Newton, Lindsay P., Liu, Chengwen, Peng, Weiyi, Sullivan, Ryan J, Lawrence, Donald P., Hodi, F. Stephen, Overwijk, Willem W., Lizée, Gregory, Murphy, George F., Hwu, Patrick, Flaherty, Keith T., Fisher, David E., Wargo, Jennifer A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752683/
https://ncbi.nlm.nih.gov/pubmed/23307859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1630
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