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Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma

The combination of BRAF-targeted agents with immune checkpoint inhibitors represents a recent advance in the treatment of melanoma, even though each of these therapeutic approaches alone has specific limitations. Increasing evidence suggests indeed the existence of a synergistic interaction between...

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Hlavní autoři: Cooper, Zachary A., Frederick, Dennie T., Ahmed, Zain, Wargo, Jennifer A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667913/
https://ncbi.nlm.nih.gov/pubmed/23762807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24320
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