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Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

Significant advances in the treatment of melanoma have been made with BRAF-targeted therapy and immune checkpoint blockade, and these strategies are now being combined empirically in clinical trials. Potential synergy is demonstrated in murine models and in analysis of longitudinal biopsies from pat...

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Pubblicato in:Oncoimmunology
Autori principali: Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292518/
https://ncbi.nlm.nih.gov/pubmed/25941608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.954956
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