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Update on use of aldesleukin for treatment of high-risk metastatic melanoma

High-dose interleukin-2 has been used for the treatment of metastatic melanoma since 1998 based on data proving durable complete responses in up to 10% of treated patients. The immunomodulatory effects of this critical cytokine have been instrumental in the development of immunotherapy for melanoma...

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Опубликовано в: :Immunotargets Ther
Главные авторы: Amaria, Rodabe N, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918260/
https://ncbi.nlm.nih.gov/pubmed/27471714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S61590
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