Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy

Autor Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.
Vydáno v Curr Oncol Rep (2016)

Monitoring immune responses in the tumor microenvironment

Autor Wargo, Jennifer A., Reddy, Sangeetha M., Reuben, Alexandre, Sharma, Padmanee
Vydáno v Curr Opin Immunol (2016)

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

Autor Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Vydáno v Immun Inflamm Dis (2017)

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy

Autor Andrews, Miles C., Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wargo, Jennifer A.
Vydáno v Front Immunol (2018)

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

Autor Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A
Vydáno v Oncoimmunology (2014)

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

Autor Cooper, Zachary A., Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A.
Vydáno v Clin Cancer Res (2015)

Raising the bar: optimizing combinations of targeted therapy and immunotherapy

Autor Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A., Cooper, Zachary A.
Vydáno v Ann Transl Med (2015)

Update on use of aldesleukin for treatment of high-risk metastatic melanoma

Autor Amaria, Rodabe N, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A
Vydáno v Immunotargets Ther (2015)

Gene targeting meets cell-based therapy: raising the tail, or merely a whimper?

Autor Cogdill, Alexandria P., Prieto, Peter A., Reuben, Alexandre, Wargo, Jennifer A.
Vydáno v Clin Cancer Res (2016)

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma

Autor Reuben, Alexandre, Amaria, Rodabe N, Cooper, Zachary A, Wargo, Jennifer A
Vydáno v J Pigment Disord (2014)

Targeted Therapies Combined with Immune Checkpoint Therapy

Autor Prieto, Peter A., Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Vydáno v Cancer J (2016)

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy

Autor Wargo, Jennifer A., Reuben, Alexandre, Cooper, Zachary A., Oh, Kevin S., Sullivan, Ryan J.
Vydáno v Semin Oncol (2015)

The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy

Autor Gopalakrishnan, Vancheswaran, Helmink, Beth A., Spencer, Christine N., Reuben, Alexandre, Wargo, Jennifer A.
Vydáno v Cancer Cell (2018)

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

Autor Kim, Teresa, Amaria, Rodabe N., Spencer, Christine, Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Vydáno v Cancer Biol Med (2014)

Interaction of molecular alterations with immune response in melanoma

Autor Sloane, Robert Szczepaniak, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Zhang, Xue, Reuben, Alexandre, Wargo, Jennifer A.
Vydáno v Cancer (2017)

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype

Autor Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean
Vydáno 2012

Working with Human Tissues for Translational Cancer Research

Autor Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wagner, Heidi E., Spencer, Christine N., Austin-Breneman, Jacob, Jiang, Hong, Cooper, Zachary A., Wargo, Jennifer A.
Vydáno v J Vis Exp (2015)

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

Autor Abbas, Hussein A., Reville, Patrick K., Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C., Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo
Vydáno v Front Immunol (2021)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

Autor Reuben, Alexandre, Cooper, Zachary A, Amaria, Rodabe N, Forget, Marie A, Haymaker, Cara, Bernatchez, Chantale, Chen, Pei-ling, Tetzlaff, Michael T, Chin, Lynda, Dwyer, Karen C, Wargo, Jennifer A
Vydáno v J Immunother Cancer (2014)

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

Autor Qin, Shuyang S., Han, Booyeon J., Williams, Alyssa, Jackson, Katherine M., Jewell, Rachel, Chacon, Alexander C., Lord, Edith M., Linehan, David C., Kim, Minsoo, Reuben, Alexandre, Gerber, Scott A., Prieto, Peter A.
Vydáno v Cancers (Basel) (2021)