Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy

per Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.
Publicat a Curr Oncol Rep (2016)

Monitoring immune responses in the tumor microenvironment

per Wargo, Jennifer A., Reddy, Sangeetha M., Reuben, Alexandre, Sharma, Padmanee
Publicat a Curr Opin Immunol (2016)

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

per Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Publicat a Immun Inflamm Dis (2017)

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy

per Andrews, Miles C., Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wargo, Jennifer A.
Publicat a Front Immunol (2018)

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

per Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A
Publicat a Oncoimmunology (2014)

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

per Cooper, Zachary A., Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A.
Publicat a Clin Cancer Res (2015)

Raising the bar: optimizing combinations of targeted therapy and immunotherapy

per Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A., Cooper, Zachary A.
Publicat a Ann Transl Med (2015)

Update on use of aldesleukin for treatment of high-risk metastatic melanoma

per Amaria, Rodabe N, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A
Publicat a Immunotargets Ther (2015)

Gene targeting meets cell-based therapy: raising the tail, or merely a whimper?

per Cogdill, Alexandria P., Prieto, Peter A., Reuben, Alexandre, Wargo, Jennifer A.
Publicat a Clin Cancer Res (2016)

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma

per Reuben, Alexandre, Amaria, Rodabe N, Cooper, Zachary A, Wargo, Jennifer A
Publicat a J Pigment Disord (2014)

Targeted Therapies Combined with Immune Checkpoint Therapy

per Prieto, Peter A., Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Publicat a Cancer J (2016)

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy

per Wargo, Jennifer A., Reuben, Alexandre, Cooper, Zachary A., Oh, Kevin S., Sullivan, Ryan J.
Publicat a Semin Oncol (2015)

The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy

per Gopalakrishnan, Vancheswaran, Helmink, Beth A., Spencer, Christine N., Reuben, Alexandre, Wargo, Jennifer A.
Publicat a Cancer Cell (2018)

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

per Kim, Teresa, Amaria, Rodabe N., Spencer, Christine, Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Publicat a Cancer Biol Med (2014)

Interaction of molecular alterations with immune response in melanoma

per Sloane, Robert Szczepaniak, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Zhang, Xue, Reuben, Alexandre, Wargo, Jennifer A.
Publicat a Cancer (2017)

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype

per Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean
Publicat 2012

Working with Human Tissues for Translational Cancer Research

per Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wagner, Heidi E., Spencer, Christine N., Austin-Breneman, Jacob, Jiang, Hong, Cooper, Zachary A., Wargo, Jennifer A.
Publicat a J Vis Exp (2015)

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

per Abbas, Hussein A., Reville, Patrick K., Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C., Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo
Publicat a Front Immunol (2021)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

per Reuben, Alexandre, Cooper, Zachary A, Amaria, Rodabe N, Forget, Marie A, Haymaker, Cara, Bernatchez, Chantale, Chen, Pei-ling, Tetzlaff, Michael T, Chin, Lynda, Dwyer, Karen C, Wargo, Jennifer A
Publicat a J Immunother Cancer (2014)

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

per Qin, Shuyang S., Han, Booyeon J., Williams, Alyssa, Jackson, Katherine M., Jewell, Rachel, Chacon, Alexander C., Lord, Edith M., Linehan, David C., Kim, Minsoo, Reuben, Alexandre, Gerber, Scott A., Prieto, Peter A.
Publicat a Cancers (Basel) (2021)