Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy

par Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.
Publié dans Curr Oncol Rep (2016)

Monitoring immune responses in the tumor microenvironment

par Wargo, Jennifer A., Reddy, Sangeetha M., Reuben, Alexandre, Sharma, Padmanee
Publié dans Curr Opin Immunol (2016)

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

par Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Publié dans Immun Inflamm Dis (2017)

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy

par Andrews, Miles C., Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wargo, Jennifer A.
Publié dans Front Immunol (2018)

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

par Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A
Publié dans Oncoimmunology (2014)

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

par Cooper, Zachary A., Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A.
Publié dans Clin Cancer Res (2015)

Raising the bar: optimizing combinations of targeted therapy and immunotherapy

par Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A., Cooper, Zachary A.
Publié dans Ann Transl Med (2015)

Update on use of aldesleukin for treatment of high-risk metastatic melanoma

par Amaria, Rodabe N, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A
Publié dans Immunotargets Ther (2015)

Gene targeting meets cell-based therapy: raising the tail, or merely a whimper?

par Cogdill, Alexandria P., Prieto, Peter A., Reuben, Alexandre, Wargo, Jennifer A.
Publié dans Clin Cancer Res (2016)

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma

par Reuben, Alexandre, Amaria, Rodabe N, Cooper, Zachary A, Wargo, Jennifer A
Publié dans J Pigment Disord (2014)

Targeted Therapies Combined with Immune Checkpoint Therapy

par Prieto, Peter A., Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Publié dans Cancer J (2016)

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy

par Wargo, Jennifer A., Reuben, Alexandre, Cooper, Zachary A., Oh, Kevin S., Sullivan, Ryan J.
Publié dans Semin Oncol (2015)

The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy

par Gopalakrishnan, Vancheswaran, Helmink, Beth A., Spencer, Christine N., Reuben, Alexandre, Wargo, Jennifer A.
Publié dans Cancer Cell (2018)

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

par Kim, Teresa, Amaria, Rodabe N., Spencer, Christine, Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Publié dans Cancer Biol Med (2014)

Interaction of molecular alterations with immune response in melanoma

par Sloane, Robert Szczepaniak, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Zhang, Xue, Reuben, Alexandre, Wargo, Jennifer A.
Publié dans Cancer (2017)

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype

par Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean
Publié 2012

Working with Human Tissues for Translational Cancer Research

par Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wagner, Heidi E., Spencer, Christine N., Austin-Breneman, Jacob, Jiang, Hong, Cooper, Zachary A., Wargo, Jennifer A.
Publié dans J Vis Exp (2015)

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

par Abbas, Hussein A., Reville, Patrick K., Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C., Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo
Publié dans Front Immunol (2021)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

par Reuben, Alexandre, Cooper, Zachary A, Amaria, Rodabe N, Forget, Marie A, Haymaker, Cara, Bernatchez, Chantale, Chen, Pei-ling, Tetzlaff, Michael T, Chin, Lynda, Dwyer, Karen C, Wargo, Jennifer A
Publié dans J Immunother Cancer (2014)

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

par Qin, Shuyang S., Han, Booyeon J., Williams, Alyssa, Jackson, Katherine M., Jewell, Rachel, Chacon, Alexander C., Lord, Edith M., Linehan, David C., Kim, Minsoo, Reuben, Alexandre, Gerber, Scott A., Prieto, Peter A.
Publié dans Cancers (Basel) (2021)