Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy

von Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.
Veröffentlicht in Curr Oncol Rep (2016)

Monitoring immune responses in the tumor microenvironment

von Wargo, Jennifer A., Reddy, Sangeetha M., Reuben, Alexandre, Sharma, Padmanee
Veröffentlicht in Curr Opin Immunol (2016)

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

von Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Veröffentlicht in Immun Inflamm Dis (2017)

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy

von Andrews, Miles C., Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wargo, Jennifer A.
Veröffentlicht in Front Immunol (2018)

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

von Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A
Veröffentlicht in Oncoimmunology (2014)

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

von Cooper, Zachary A., Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A.
Veröffentlicht in Clin Cancer Res (2015)

Raising the bar: optimizing combinations of targeted therapy and immunotherapy

von Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A., Cooper, Zachary A.
Veröffentlicht in Ann Transl Med (2015)

Update on use of aldesleukin for treatment of high-risk metastatic melanoma

von Amaria, Rodabe N, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A
Veröffentlicht in Immunotargets Ther (2015)

Gene targeting meets cell-based therapy: raising the tail, or merely a whimper?

von Cogdill, Alexandria P., Prieto, Peter A., Reuben, Alexandre, Wargo, Jennifer A.
Veröffentlicht in Clin Cancer Res (2016)

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma

von Reuben, Alexandre, Amaria, Rodabe N, Cooper, Zachary A, Wargo, Jennifer A
Veröffentlicht in J Pigment Disord (2014)

Targeted Therapies Combined with Immune Checkpoint Therapy

von Prieto, Peter A., Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Veröffentlicht in Cancer J (2016)

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy

von Wargo, Jennifer A., Reuben, Alexandre, Cooper, Zachary A., Oh, Kevin S., Sullivan, Ryan J.
Veröffentlicht in Semin Oncol (2015)

The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy

von Gopalakrishnan, Vancheswaran, Helmink, Beth A., Spencer, Christine N., Reuben, Alexandre, Wargo, Jennifer A.
Veröffentlicht in Cancer Cell (2018)

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

von Kim, Teresa, Amaria, Rodabe N., Spencer, Christine, Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Veröffentlicht in Cancer Biol Med (2014)

Interaction of molecular alterations with immune response in melanoma

von Sloane, Robert Szczepaniak, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Zhang, Xue, Reuben, Alexandre, Wargo, Jennifer A.
Veröffentlicht in Cancer (2017)

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype

von Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean
Veröffentlicht 2012

Working with Human Tissues for Translational Cancer Research

von Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wagner, Heidi E., Spencer, Christine N., Austin-Breneman, Jacob, Jiang, Hong, Cooper, Zachary A., Wargo, Jennifer A.
Veröffentlicht in J Vis Exp (2015)

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

von Abbas, Hussein A., Reville, Patrick K., Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C., Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo
Veröffentlicht in Front Immunol (2021)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

von Reuben, Alexandre, Cooper, Zachary A, Amaria, Rodabe N, Forget, Marie A, Haymaker, Cara, Bernatchez, Chantale, Chen, Pei-ling, Tetzlaff, Michael T, Chin, Lynda, Dwyer, Karen C, Wargo, Jennifer A
Veröffentlicht in J Immunother Cancer (2014)

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

von Qin, Shuyang S., Han, Booyeon J., Williams, Alyssa, Jackson, Katherine M., Jewell, Rachel, Chacon, Alexander C., Lord, Edith M., Linehan, David C., Kim, Minsoo, Reuben, Alexandre, Gerber, Scott A., Prieto, Peter A.
Veröffentlicht in Cancers (Basel) (2021)