Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy

por Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.
Publicado en Curr Oncol Rep (2016)

Monitoring immune responses in the tumor microenvironment

por Wargo, Jennifer A., Reddy, Sangeetha M., Reuben, Alexandre, Sharma, Padmanee
Publicado en Curr Opin Immunol (2016)

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

por Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Publicado en Immun Inflamm Dis (2017)

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy

por Andrews, Miles C., Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wargo, Jennifer A.
Publicado en Front Immunol (2018)

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

por Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A
Publicado en Oncoimmunology (2014)

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

por Cooper, Zachary A., Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A.
Publicado en Clin Cancer Res (2015)

Raising the bar: optimizing combinations of targeted therapy and immunotherapy

por Reuben, Alexandre, Austin-Breneman, Jacob, Wargo, Jennifer A., Cooper, Zachary A.
Publicado en Ann Transl Med (2015)

Update on use of aldesleukin for treatment of high-risk metastatic melanoma

por Amaria, Rodabe N, Reuben, Alexandre, Cooper, Zachary A, Wargo, Jennifer A
Publicado en Immunotargets Ther (2015)

Gene targeting meets cell-based therapy: raising the tail, or merely a whimper?

por Cogdill, Alexandria P., Prieto, Peter A., Reuben, Alexandre, Wargo, Jennifer A.
Publicado en Clin Cancer Res (2016)

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma

por Reuben, Alexandre, Amaria, Rodabe N, Cooper, Zachary A, Wargo, Jennifer A
Publicado en J Pigment Disord (2014)

Targeted Therapies Combined with Immune Checkpoint Therapy

por Prieto, Peter A., Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Publicado en Cancer J (2016)

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy

por Wargo, Jennifer A., Reuben, Alexandre, Cooper, Zachary A., Oh, Kevin S., Sullivan, Ryan J.
Publicado en Semin Oncol (2015)

The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy

por Gopalakrishnan, Vancheswaran, Helmink, Beth A., Spencer, Christine N., Reuben, Alexandre, Wargo, Jennifer A.
Publicado en Cancer Cell (2018)

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

por Kim, Teresa, Amaria, Rodabe N., Spencer, Christine, Reuben, Alexandre, Cooper, Zachary A., Wargo, Jennifer A.
Publicado en Cancer Biol Med (2014)

Interaction of molecular alterations with immune response in melanoma

por Sloane, Robert Szczepaniak, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Zhang, Xue, Reuben, Alexandre, Wargo, Jennifer A.
Publicado en Cancer (2017)

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype

por Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean
Publicado 2012

Working with Human Tissues for Translational Cancer Research

por Reuben, Alexandre, Gopalakrishnan, Vancheswaran, Wagner, Heidi E., Spencer, Christine N., Austin-Breneman, Jacob, Jiang, Hong, Cooper, Zachary A., Wargo, Jennifer A.
Publicado en J Vis Exp (2015)

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

por Abbas, Hussein A., Reville, Patrick K., Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C., Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo
Publicado en Front Immunol (2021)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

por Reuben, Alexandre, Cooper, Zachary A, Amaria, Rodabe N, Forget, Marie A, Haymaker, Cara, Bernatchez, Chantale, Chen, Pei-ling, Tetzlaff, Michael T, Chin, Lynda, Dwyer, Karen C, Wargo, Jennifer A
Publicado en J Immunother Cancer (2014)

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

por Qin, Shuyang S., Han, Booyeon J., Williams, Alyssa, Jackson, Katherine M., Jewell, Rachel, Chacon, Alexander C., Lord, Edith M., Linehan, David C., Kim, Minsoo, Reuben, Alexandre, Gerber, Scott A., Prieto, Peter A.
Publicado en Cancers (Basel) (2021)