PD-1 and BTLA and CD8(+) T-cell “exhaustion” in cancer: “Exercising” an alternative viewpoint

Por Haymaker, Cara, Wu, Richard, Bernatchez, Chantale, Radvanyi, Laszlo
Publicado em 2012

You can run but you can't hide: tracking T cells in metastatic melanoma patients treated with tumor-infiltrating lymphocytes

Por Haymaker, Cara, Forget, Marie-Andrée, Creasy, Caitlin, Ritthipichai, Krit, Hwu, Patrick, Bernatchez, Chantale
Publicado no J Immunother Cancer (2015)

Modification of BTLA signaling motifs in TIL exhibits positive signals that mediate anti-tumor control

Por Ritthipichai, Krit, Haymaker, Cara, Hailemichael, Yared, Zhang, Minying, Nurieva, Roza, Hwu, Patrick, Bernatchez, Chantale
Publicado no J Immunother Cancer (2015)

Preclinical development of tumor-infiltrating lymphocyte therapy for ovarian cancer

Por Sakellariou-Thompson, Donastas, Haymaker, Cara, Forget, Marie-Andree, Jazaeri, Amir, Hwu, Patrick, Bernatchez, Chantale
Publicado no J Immunother Cancer (2015)

Adoptive T-cell Therapy Using Autologous Tumor-infiltrating Lymphocytes for Metastatic Melanoma: Current Status and Future Outlook

Por Wu, Richard, Forget, Marie-Andree, Chacon, Jessica, Bernatchez, Chantale, Haymaker, Cara, Chen, Jie Qing, Hwu, Patrick, Radvanyi, Laszlo
Publicado em 2012

Single-cell motility and gene expression signature as predictors of the overall survival of act in melanoma patients

Por Martinez-Paniagua, Melisa, Haymaker, Cara, Adolacion, Jay R, Radvanyi, Laszlo, Hwu, Patrick, Roysam, Badrinath, Bernatchez, Chantale, Varadarajan, Navin
Publicado no J Immunother Cancer (2015)

Immune-Modulation by Epidermal Growth Factor Receptor Inhibitors: Implication on Anti-Tumor Immunity in Lung Cancer

Por Im, Jin S., Herrmann, Amanda C., Bernatchez, Chantale, Haymaker, Cara, Molldrem, Jeffrey J., Hong, Waun Ki, Perez-Soler, Roman
Publicado no PLoS One (2016)

Batf is important for IL-4 expression in T follicular helper cells

Por Sahoo, Anupama, Alekseev, Andrei, Tanaka, Kentaro, Obertas, Lidiya, Lerman, Beatrisa, Haymaker, Cara, Clise-Dwyer, Karen, McMurray, John S., Nurieva, Roza
Publicado no Nat Commun (2015)

Development of novel combinations of targeted and immunotherapies by understanding immune resistance using a high throughput assay of T cell mediated cytotoxicity

Por Malu, Shruti, Mbofung, Rina, Khalili, Jahan, Satani, Nikunj, Forget, Marie-Andrée, Haymaker, Cara, Muller, Florian, Bernatchez, Chantale, Radvanyi, Laszlo, Hwu, Patrick
Publicado em 2013

Identification of predictive biomarker signatures in melanoma tumors associated with response to tumor-infiltrating lymphocyte (TIL) therapy

Por Chen, Jie Qing, Creasy, Caitlin, Cabala, Carlos Antonio Torres, Ekmekcioglu, Suhendan, Maiti, Sourindra N, Roszik, Jason, Haymaker, Cara, Bernatchez, Chantale, Hwu, Patrick, Radvanyi, Laszlo
Publicado em 2013

Uncovering a novel function of BTLA on tumor-infiltrating CD8+ T cells

Por Haymaker, Cara, Wu, Richard, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andree, Chen, Jie Qing, Liu, Hiu, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo
Publicado em 2013

Antigen-Specific Effector CD4 T Lymphocytes School Lamina Propria Dendritic Cells to Transfer Innate Tolerance

Por Cascio, Jason A., Haymaker, Cara L., Divekar, Rohit D., Zaghouani, Sarah, Khairallah, Marie-Therese, Wan, Xiaoxiao, Rowland, Linda M., Dhakal, Mermagya, Chen, Weirong, Zaghouani, Habib
Publicado em 2013

Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn’s disease: a case...

Por Uemura, Marc, Trinh, Van A., Haymaker, Cara, Jackson, Natalie, Kim, Dae Won, Allison, James P., Sharma, Padmanee, Vence, Luis, Bernatchez, Chantale, Hwu, Patrick, Diab, Adi
Publicado no J Hematol Oncol (2016)

Delayed maturation of an IL-12–producing dendritic cell subset explains the early Th2 bias in neonatal immunity

Por Lee, Hyun-Hee, Hoeman, Christine M., Hardaway, John C., Guloglu, F. Betul, Ellis, Jason S., Jain, Renu, Divekar, Rohit, Tartar, Danielle M., Haymaker, Cara L., Zaghouani, Habib
Publicado em 2008

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

Por Forget, Marie-Andrée, Haymaker, Cara, Dennison, Jennifer B, Toth, Christopher, Maiti, Sourindra, Fulbright, Orenthial J, Cooper, Laurence J N, Hwu, Patrick, Radvanyi, Laszlo G, Bernatchez, Chantale
Publicado no Oncoimmunology (2015)

Fetal Exposure to High Avidity T Cell Receptor Ligand Enhances Expansion of Peripheral T Regulatory Cells

Por Yu, Ping, Haymaker, Cara L., Divekar, Rohit D., Ellis, Jason S., Hardaway, John, Jain, Renu, Tartar, Danielle M., Hoeman, Christine M., Cascio, Jason A., Ostermeier, Austin, Zaghouani, Habib
Publicado em 2008

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

Por Haymaker, Cara L, Wu, Richard C, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andrée, Chen, Jie Qing, Liu, Hui, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo G
Publicado no Oncoimmunology (2015)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

Por Reuben, Alexandre, Cooper, Zachary A, Amaria, Rodabe N, Forget, Marie A, Haymaker, Cara, Bernatchez, Chantale, Chen, Pei-ling, Tetzlaff, Michael T, Chin, Lynda, Dwyer, Karen C, Wargo, Jennifer A
Publicado no J Immunother Cancer (2014)

A case report of Grover’s disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1

Por Uemura, Marc, Faisal, Faa’k, Haymaker, Cara, McQuail, Natalie, Sirmans, Elizabeth, Hudgens, Courtney W., Barbara, Lydia, Bernatchez, Chantale, Curry, Jonathan L., Hwu, Patrick, Tetzlaff, Michael T., Diab, Adi
Publicado no J Immunother Cancer (2016)

Erratum to: A case report of Grover’s disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1

Por Uemura, Marc, Fa’ak, Faisal, Haymaker, Cara, McQuail, Natalie, Sirmans, Elizabeth, Hudgens, Courtney W., Barbara, Lydia, Bernatchez, Chantale, Curry, Jonathan L., Hwu, Patrick, Tetzlaff, Michael T., Diab, Adi
Publicado no J Immunother Cancer (2017)