Advances in the Treatment of Metastatic Melanoma: Adoptive T Cell Therapy

Por Bernatchez, Chantale, Radvanyi, Laszlo G., Hwu, Patrick
Publicado em 2012

New insights on the role of CD8(+)CD57(+) T-cells in cancer

Por Wu, Richard C., Hwu, Patrick, Radvanyi, Laszlo G.
Publicado em 2012

Development and application of ‘phosphoflow’ as a tool for immunomonitoring

Por Wu, Sheng, Jin, Lei, Vence, Luis, Radvanyi, Laszlo G
Publicado em 2010

Advances in the Development of Cancer Immunotherapies

Por Gao, Jianjun, Bernatchez, Chantale, Sharma, Padmanee, Radvanyi, Laszlo G., Hwu, Patrick
Publicado em 2012

Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy

Por Chacon, Jessica Ann, Pilon-Thomas, Shari, Sarnaik, Amod A, Radvanyi, Laszlo G
Publicado em 2013

Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2

Por Sim, Geok Choo, Wu, Sheng, Jin, Lei, Hwu, Patrick, Radvanyi, Laszlo G.
Publicado no Oncotarget (2016)

A new approach for the large-scale generation of mature dendritic cells from adherent PBMC using roller bottle technology

Por Campbell-Anson, Ryan E, Kentor, Diane, Wang, Yi J, Bushnell, Kathryn M, Li, Yufeng, Vence, Luis M, Radvanyi, Laszlo G
Publicado em 2008

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

Por Forget, Marie-Andrée, Haymaker, Cara, Dennison, Jennifer B, Toth, Christopher, Maiti, Sourindra, Fulbright, Orenthial J, Cooper, Laurence J N, Hwu, Patrick, Radvanyi, Laszlo G, Bernatchez, Chantale
Publicado no Oncoimmunology (2015)

Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals

Por Bernatchez, Chantale, Zhu, Kuichin, Li, Yufeng, Andersson, Helen, Ionnides, Constantin, Fernandez-Vina, Marcelo, Cano, Pedro, Cooper, Laurence, Abbruzzese, James, Hwu, Patrick, Chang, David Z., Radvanyi, Laszlo G.
Publicado em 2011

Genetically modified artificial antigen-presenting cells (aAPC) for expansion of melanoma tumor infiltrating lymphocytes with optimal properties for adoptive cell therapy

Por Forget, Marie-Andrée, Malu, Shruti, Liu, Hiu, Toth, Christopher, Maiti, Sourindra, Kale, Charuta, Bernatchez, Chantale, Huls, Helen, Wang, Ena, Hwu, Patrick, Cooper, Laurence J, Radvanyi, Laszlo G
Publicado em 2013

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

Por Haymaker, Cara L, Wu, Richard C, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andrée, Chen, Jie Qing, Liu, Hui, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo G
Publicado no Oncoimmunology (2015)

Detection and Characterization of a Novel Subset of CD8(+)CD57(+) T-cells in Metastatic Melanoma with an Incompletely-Differentiated Phenotype

Por Wu, Richard C., Liu, Shujuan, Chacon, Jessica A., Wu, Sheng, Li, Yufeng, Sukhumalchandra, Pariya, Murray, James L., Molldrem, Jeffrey J., Hwu, Patrick, Pircher, Hanspeter, Lizée, Gregory, Radvanyi, Laszlo G.
Publicado em 2012

Activation and propagation of tumor infiltrating lymphocytes on clinical-grade designer artificial antigen presenting cells for adoptive immunotherapy of melanoma

Por Forget, Marie-Andrée, Malu, Shruti, Liu, Hui, Toth, Christopher, Maiti, Sourindra, Kale, Charuta, Haymaker, Cara, Bernatchez, Chantale, Huls, Helen, Wang, Ena, Marincola, Francesco M., Hwu, Patrick, Cooper, Laurence J. N., Radvanyi, Laszlo G.
Publicado em 2014

BRAF(V600E) co-opts a conserved MHC class I internalization pathway to diminish antigen presentation and CD8+ T-cell recognition of melanoma

Por Bradley, Sherille D., Chen, Zeming, Melendez, Brenda, Talukder, Amjad, Khalili, Jahan S., Rodriguez-Cruz, Tania, Liu, Shujuan, Whittington, Mayra, Deng, Wanleng, Li, Fenge, Bernatchez, Chantale, Radvanyi, Laszlo G., Davies, Michael A., Hwu, Patrick, Lizée, Gregory
Publicado no Cancer Immunol Res (2015)

An Antibody-based Blood Test Utilizing a Panel of Biomarkers as a New Method for Improved Breast Cancer Diagnosis

Por Yahalom, Galit, Weiss, Daria, Novikov, Ilya, Bevers, Therese B., Radvanyi, Laszlo G., Liu, Mei, Piura, Benjamin, Iacobelli, Stefano, Sandri, Maria T., Cassano, Enrico, Allweis, Tanir M., Bitterman, Arie, Engelman, Pnina, Vence, Luis M., Rosenberg, Marvin M.
Publicado em 2013

2E8 Binds to the High Affinity I-domain in a Metal Ion-dependent Manner: A SECOND GENERATION MONOCLONAL ANTIBODY SELECTIVELY TARGETING ACTIVATED LFA-1

Por Carreño, Roberto, Brown, Wells S., Li, Dan, Hernandez, Jessica A., Wang, Yang, Kim, Tae Kon, Craft, John W., Komanduri, Krishna V., Radvanyi, Laszlo G., Hwu, Patrick, Molldrem, Jeffrey J., Legge, Glen B., McIntyre, Bradley W., Ma, Qing
Publicado em 2010

Lovastatin inhibits T cell proliferation while preserving the cytolytic function of EBV-, CMV- and MART-1-specific CTLs

Por Li, Dan, Li, Yufeng, Hernandez, Jessica A., Patenia, Rebecca, Kim, Tae Kon, Khalili, Jahan, Dougherty, Mark C., Hanley, Patrick J., Bollard, Catherine M., Komanduri, Krishna V., Hwu, Patrick, Champlin, Richard E., Radvanyi, Laszlo G., Molldrem, Jeffrey J., Ma, Qing
Publicado no J Immunother (2010)

Intrathecal administration of tumor-infiltrating lymphocytes is well tolerated in a patient with leptomeningeal disease from metastatic melanoma: A case report

Por Glitza, Isabella C., Haymaker, Cara, Bernatchez, Chantale, Vence, Luis, Rohlfs, Michelle, Richard, Jessie, Lacey, Carol, Mansaray, Rahmatu, Fulbright, Orenthial J., Ramachandran, Renjith, Toth, Christopher, Wardell, Seth, Patel, Sapna P., Woodman, Scott E., Hwu, Wen-Jen, Radvanyi, Laszlo G., Davies, Michael A., Papadopoulos, Nicholas E., Hwu, Patrick
Publicado no Cancer Immunol Res (2015)

MUC1 glycopeptide epitopes predicted by computational glycomics

Por SONG, WEI, DELYRIA, ELIZABETH S., CHEN, JIEQING, HUANG, WEI, LEE, JUN SOO, MITTENDORF, ELIZABETH A., IBRAHIM, NUHAD, RADVANYI, LASZLO G., LI, YUNSEN, LU, HONGZHOU, XU, HUAXI, SHI, YINQIANG, WANG, LAI-XI, ROSS, JEREMY A., RODRIGUES, SILAS P., ALMEIDA, IGOR C., YANG, XIFENG, QU, JIN, SCHOCKER, NATHANIEL S., MICHAEL, KATJA, ZHOU, DAPENG
Publicado em 2012

Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapy

Por Joseph, Richard W., Peddareddigari, Vijay R., Liu, Ping, Miller, Priscilla W., Overwijk, Willem W., Bekele, Nebiyou B., Ross, Merrick I., Lee, Jeffrey E., Gershenwald, Jeffrey E., Lucci, Anthony, Prieto, Victor G., McMannis, John D., Papadopoulos, Nicholas, Kim, Kevin, Homsi, Jade, Bedikian, Agop, Hwu, Wen-Jen, Hwu, Patrick, Radvanyi, Laszlo G.
Publicado em 2011