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Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals

Survivin is a universal tumor antigen that is being currently targeted in vaccine app roaches against cancer. Our study here examined the immunogenicity of a novel variant of an HLA-A0201-binding decamer peptide from region 95-104 of Survivin (ELMLGEFLKL) with a T→M modification at position 3 in the...

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Bibliografski detalji
Glavni autori: Bernatchez, Chantale, Zhu, Kuichin, Li, Yufeng, Andersson, Helen, Ionnides, Constantin, Fernandez-Vina, Marcelo, Cano, Pedro, Cooper, Laurence, Abbruzzese, James, Hwu, Patrick, Chang, David Z., Radvanyi, Laszlo G.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070784/
https://ncbi.nlm.nih.gov/pubmed/21320548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.01.115
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