Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer

Por Peng, Weiyi, Lizée, Gregory, Hwu, Patrick
Publicado em 2013

Strong emerging rationale for combining oncogene-targeted agents with immunotherapy

Por Yang, Yan, Lizée, Gregory, Hwu, Patrick
Publicado em 2013

Forging a link between oncogenic signaling and immunosuppression in melanoma

Por Khalili, Jahan S., Hwu, Patrick, Lizée, Gregory
Publicado em 2013

Trouble at the core: BRAF(V600E) drives multiple modes of T-cell suppression in melanoma

Por Bradley, Sherille D., Melendez, Brenda, Talukder, Amjad, Lizée, Gregory
Publicado no Oncoimmunology (2015)

Exploiting Tumor Neoantigens to Target Cancer Evolution: Current Challenges and Promising Therapeutic Approaches

Por Gupta, Ravi G., Li, Fenge, Roszik, Jason, Lizée, Gregory
Publicado no Cancer Discov (2021)

General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept

Por Antunes, Dinler A., Devaurs, Didier, Moll, Mark, Lizée, Gregory, Kavraki, Lydia E.
Publicado no Sci Rep (2018)

Markov state modeling reveals alternative unbinding pathways for peptide–MHC complexes

Por Abella, Jayvee R., Antunes, Dinler, Jackson, Kyle, Lizée, Gregory, Clementi, Cecilia, Kavraki, Lydia E.
Publicado no Proc Natl Acad Sci U S A (2020)

MHC Class I Endosomal and Lysosomal Trafficking Coincides with Exogenous Antigen Loading in Dendritic Cells

Por Basha, Genc, Lizée, Gregory, Reinicke, Anna T., Seipp, Robyn P., Omilusik, Kyla D., Jefferies, Wilfred A.
Publicado em 2008

DINC 2.0: a new protein-peptide docking webserver using an incremental approach

Por Antunes, Dinler A., Moll, Mark, Devaurs, Didier, Jackson, Kyle R., Lizée, Gregory, Kavraki, Lydia E.
Publicado no Cancer Res (2017)

Natural Splice Variant of MHC Class I Cytoplasmic Tail Enhances Dendritic Cell-Induced CD8(+) T-Cell Responses and Boosts Anti-Tumor Immunity

Por Rodríguez-Cruz, Tania G., Liu, Shujuan, Khalili, Jahan S., Whittington, Mayra, Zhang, Minying, Overwijk, Willem, Lizée, Gregory
Publicado em 2011

Constitutive Aberrant Endogenous Interleukin-1 Facilitates Inflammation and Growth in Human Melanoma

Por Qin, Yong, Ekmekcioglu, Suhendan, Liu, Ping, Duncan, Lyn M., Lizée, Gregory, Poindexter, Nancy, Grimm, Elizabeth A.
Publicado em 2011

Using parallelized incremental meta-docking can solve the conformational sampling issue when docking large ligands to proteins

Por Devaurs, Didier, Antunes, Dinler A, Hall-Swan, Sarah, Mitchell, Nicole, Moll, Mark, Lizée, Gregory, Kavraki, Lydia E
Publicado no BMC Mol Cell Biol (2019)

Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40

Por Yang, Yan, Liu, Chengwen, Peng, Weiyi, Lizée, Gregory, Overwijk, Willem W., Liu, Yang, Woodman, Scott E., Hwu, Patrick
Publicado em 2012

NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy

Por Yoshihama, Sayuri, Cho, Steven X., Yeung, Jason, Pan, Xuedong, Lizee, Gregory, Konganti, Kranti, Johnson, Valen E., Kobayashi, Koichi S.
Publicado no Sci Rep (2021)

Dendritic Cells Strongly Boost the Antitumor Activity of Adoptively Transferred T Cells In vivo

Por Lou, Yanyan, Wang, Gang, Lizée, Gregory, Kim, Grace J., Finkelstein, Steven E., Feng, Chiguang, Restifo, Nicholas P., Hwu, Patrick
Publicado em 2004

Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ and GNA11 Dependent Manner

Por Khalili, Jahan S., Yu, Xiaoxing, Wang, Ji, Hayes, Brendan C., Davies, Michael A., Lizee, Gregory, Esmaeli, Bita, Woodman, Scott E.
Publicado em 2012

Rapid tumor regression in an Asian lung cancer patient following personalized neo-epitope peptide vaccination

Por Li, Fenge, Chen, Caixia, Ju, Tao, Gao, Junqin, Yan, Jun, Wang, Peng, Xu, Qiang, Hwu, Patrick, Du, Xueming, Lizée, Gregory
Publicado no Oncoimmunology (2016)

HLA-Arena: A Customizable Environment for the Structural Modeling and Analysis of Peptide-HLA Complexes for Cancer Immunotherapy

Por Antunes, Dinler A., Abella, Jayvee R., Hall-Swan, Sarah, Devaurs, Didier, Conev, Anja, Moll, Mark, Lizée, Gregory, Kavraki, Lydia E.
Publicado no JCO Clin Cancer Inform (2020)

Intralymphatic Dendritic Cell Vaccination Induces Tumor Antigen–Specific, Skin-Homing T Lymphocytes

Por Grover, Amelia, Kim, Grace J., Lizée, Gregory, Tschoi, Mary, Wang, Gang, Wunderlich, John R., Rosenberg, Steven A., Hwang, Sam T., Hwu, Patrick
Publicado em 2006

PD-1 BLOCKADE ENHANCES T CELL MIGRATION TO TUMORS BY ELEVATING IFN-γ INDUCIBLE CHEMOKINES

Por Peng, Weiyi, Liu, Chengwen, Xu, Chunyu, Lou, Yanyan, Chen, Jieqing, Yang, Yan, Yagita, Hideo, Overwijk, Willem W., Lizée, Gregory, Radvanyi, Laszlo, Hwu, Patrick
Publicado em 2012