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Trouble at the core: BRAF(V600E) drives multiple modes of T-cell suppression in melanoma

Several studies have demonstrated that oncogenic BRAF((V600E)) promotes T-cell suppression in melanoma by upregulating the transcription of a multitude of immunomodulatory chemokine and cytokine genes. BRAF((V600E)) has now been shown to act even more directly to evade cytotoxic T-cell recognition,...

詳細記述

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書誌詳細
出版年:Oncoimmunology
主要な著者: Bradley, Sherille D., Melendez, Brenda, Talukder, Amjad, Lizée, Gregory
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801458/
https://ncbi.nlm.nih.gov/pubmed/27057458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1078966
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