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Trouble at the core: BRAF(V600E) drives multiple modes of T-cell suppression in melanoma
Several studies have demonstrated that oncogenic BRAF((V600E)) promotes T-cell suppression in melanoma by upregulating the transcription of a multitude of immunomodulatory chemokine and cytokine genes. BRAF((V600E)) has now been shown to act even more directly to evade cytotoxic T-cell recognition,...
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| Publicado no: | Oncoimmunology |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801458/ https://ncbi.nlm.nih.gov/pubmed/27057458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1078966 |
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