MHC Class I Endosomal and Lysosomal Trafficking Coincides with Exogenous Antigen Loading in Dendritic Cells

BACKGROUND: Cross-presentation by dendritic cells (DCs) is a crucial prerequisite for effective priming of cytotoxic T-cell responses against bacterial, viral and tumor antigens; however, this antigen presentation pathway remains poorly defined. METHODOLOGY/PRINCIPAL FINDINGS: In order to develop a...

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Detalhes bibliográficos
Main Authors: Basha, Genc, Lizée, Gregory, Reinicke, Anna T., Seipp, Robyn P., Omilusik, Kyla D., Jefferies, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532750/
https://ncbi.nlm.nih.gov/pubmed/18802471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003247
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