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A CD74-DEPENDENT MHC CLASS I ENDOLYSOSOMAL CROSS-PRESENTATION PATHWAY
Immune responses are initiated and primed by dendritic cells (DCs) that cross-present exogenous antigen. The CD74 (invariant chain) chaperone protein is thought to exclusively promote DC priming in the context of MHC class II. However, we demonstrate herein a CD74-dependent MHC class I cross-present...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933585/ https://ncbi.nlm.nih.gov/pubmed/22306692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2225 |
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