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General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept
The class I major histocompatibility complex (MHC) is capable of binding peptides derived from intracellular proteins and displaying them at the cell surface. The recognition of these peptide-MHC (pMHC) complexes by T-cells is the cornerstone of cellular immunity, enabling the elimination of infecte...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847594/ https://ncbi.nlm.nih.gov/pubmed/29531253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22173-4 |
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