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Detection and Characterization of a Novel Subset of CD8(+)CD57(+) T-cells in Metastatic Melanoma with an Incompletely-Differentiated Phenotype

PURPOSE: Tumor-specific T-cells are frequently induced naturally in melanoma patients and infiltrate tumors. It is enigmatic why these patients fail to experience tumor regression. Given that CD8(+) T cells mediate antigen-specific killing of tumor cells, the focus of this study was to identify alte...

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Detalhes bibliográficos
Main Authors: Wu, Richard C., Liu, Shujuan, Chacon, Jessica A., Wu, Sheng, Li, Yufeng, Sukhumalchandra, Pariya, Murray, James L., Molldrem, Jeffrey J., Hwu, Patrick, Pircher, Hanspeter, Lizée, Gregory, Radvanyi, Laszlo G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343210/
https://ncbi.nlm.nih.gov/pubmed/22307139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2034
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