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Immune-Modulation by Epidermal Growth Factor Receptor Inhibitors: Implication on Anti-Tumor Immunity in Lung Cancer

Skin toxicity is the most common toxicity caused by Epidermal Growth Factor Receptor (EGFR) inhibitors, and has been associated with clinical efficacy. As EGFR inhibitors enhance the expression of antigen presenting molecules in affected skin keratinocytes, they may concurrently facilitate neo-antig...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Im, Jin S., Herrmann, Amanda C., Bernatchez, Chantale, Haymaker, Cara, Molldrem, Jeffrey J., Hong, Waun Ki, Perez-Soler, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965069/
https://ncbi.nlm.nih.gov/pubmed/27467256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160004
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