Friend of GATA suppresses the GATA-induced transcription of hepcidin in hepatocytes through a GATA-regulatory element in the HAMP promoter

Por Bagu, Edward T, Santos, Manuela M
Publicado em 2011

Is the Iron Donor Lipocalin 2 Implicated in the Pathophysiology of Hereditary Hemochromatosis?

Por Huang, Hua, Akira, Shizuo, Santos, Manuela M.
Publicado em 2009

Anemia upregulates lipocalin 2 in the liver and serum

Por Jiang, Wenlei, Constante, Marco, Santos, Manuela M.
Publicado em 2008

Isolation of Murine Peritoneal Macrophages to Carry Out Gene Expression Analysis Upon Toll-like Receptors Stimulation

Por Layoun, Antonio, Samba, Macha, Santos, Manuela M.
Publicado no J Vis Exp (2015)

Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli

Por Huang, Hua, Constante, Marco, Layoun, Antonio, Santos, Manuela M.
Publicado em 2009

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

Por Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Publicado no Immun Inflamm Dis (2017)

Contributions of β2-microglobulin–dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(−/−) and β2mRag1(−/−) double knock-out mice

Por Miranda, Carlos J., Makui, Hortence, Andrews, Nancy C., Santos, Manuela M.
Publicado em 2003

Repression of Repulsive Guidance Molecule C during Inflammation Is Independent of Hfe and Involves Tumor Necrosis Factor-α

Por Constante, Marco, Wang, Dongmei, Raymond, Valérie-Ann, Bilodeau, Marc, Santos, Manuela M.
Publicado em 2007

Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading

Por Makui, Hortence, Soares, Ricardo J., Jiang, Wenlei, Constante, Marco, Santos, Manuela M.
Publicado em 2005

Dietary Heme Induces Gut Dysbiosis, Aggravates Colitis, and Potentiates the Development of Adenomas in Mice

Por Constante, Marco, Fragoso, Gabriela, Calvé, Annie, Samba-Mondonga, Macha, Santos, Manuela M.
Publicado no Front Microbiol (2017)

MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice

Por Layoun, Antonio, Samba-Mondonga, Macha, Fragoso, Gabriela, Calvé, Annie, Santos, Manuela M.
Publicado no Front Physiol (2018)

Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation

Por Constante, Marco, Jiang, Wenlei, Wang, Dongmei, Raymond, Valérie-Ann, Bilodeau, Marc, Santos, Manuela M.
Publicado em 2006

Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado–Joseph disease (MJD) gene

Por Costa, Maria do Carmo, Gomes-da-Silva, Joana, Miranda, Carlos J., Sequeiros, Jorge, Santos, Manuela M., Maciel, Patrícia
Publicado em 2004

Iron Overload and Heart Fibrosis in Mice Deficient for Both β2-Microglobulin and Rag1

Por Santos, Manuela M., de Sousa, Maria, Rademakers, Luke H. P. M., Clevers, Hans, Marx, J. J. M., Schilham, Marco W.
Publicado em 2000

Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosis

Por Gannon, Philippe O., Medelci, Sanae, Le Page, Cécile, Beaulieu, Martin, Provencher, Diane M., Mes-Masson, Anne-Marie, Santos, Manuela M.
Publicado em 2011

Gene expression profiling in frataxin deficient mice: Microarray evidence for significant expression changes without detectable neurodegeneration

Por Coppola, Giovanni, Choi, Sang-Hyun, Santos, Manuela M., Miranda, Carlos J., Tentler, Dmitri, Wexler, Eric M., Pandolfo, Massimo, Geschwind, Daniel H.
Publicado em 2006

Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation

Por Fillebeen, Carine, Gkouvatsos, Konstantinos, Fragoso, Gabriela, Calvé, Annie, Garcia-Santos, Daniel, Buffler, Marzell, Becker, Christiane, Schümann, Klaus, Ponka, Prem, Santos, Manuela M., Pantopoulos, Kostas
Publicado no Haematologica (2015)

Response to: Dietary and pharmacological factors affecting iron absorption in mice and man

Por Fillebeen, Carine, Gkouvatsos, Konstantinos, Fragoso, Gabriela, Calvé, Annie, Garcia-Santos, Daniel, Buffler, Marzell, Becker, Christiane, Schümann, Klaus, Ponka, Prem, Santos, Manuela M., Pantopoulos, Kostas
Publicado no Haematologica (2016)

Exclusion of mutations in the PRNP, JPH3, TBP, ATN1, CREBBP, POU3F2 and FTL genes as a cause of disease in Portuguese patients with a Huntington-like phenotype

Por Costa, Maria do Carmo, Teixeira-Castro, Andreia, Constante, Marco, Magalhães, Marina, Magalhães, Paula, Cerqueira, Joana, Vale, José, Passão, Vitorina, Barbosa, Célia, Robalo, Conceição, Coutinho, Paula, Barros, José, Santos, Manuela M., Sequeiros, Jorge, Maciel, Patrícia
Publicado em 2006