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Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation
Hepcidin is a negative regulator of iron absorption produced mainly by the liver in response to changes in iron stores and inflammation, and its levels have been shown to regulate the intestinal basolateral iron transporter ferroportin1 (Fp1). Hereditary hemochromatosis patients and Hfe-deficient mi...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891007/ https://ncbi.nlm.nih.gov/pubmed/16565419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00092.2006 |
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