Hepcidin in iron overload disorders

Hepcidin is the principal regulator of iron absorption in humans. The peptide inhibits cellular iron efflux by binding to the iron export channel ferroportin and inducing its internalization and degradation. Either hepcidin deficiency or alterations in its target, ferroportin, would be expected to r...

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Xehetasun bibliografikoak
Egile Nagusiak: Papanikolaou, George, Tzilianos, Michalis, Christakis, John I., Bogdanos, Dionisios, Tsimirika, Konstantina, MacFarlane, Julie, Goldberg, Y. Paul, Sakellaropoulos, Nikos, Ganz, Tomas, Nemeth, Elizabeta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: © 2005 by The American Society of Hematology 2005
Gaiak:
Red Cells
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895089/
https://ncbi.nlm.nih.gov/pubmed/15671438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4844
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