Hepcidin in iron overload disorders

Hepcidin is the principal regulator of iron absorption in humans. The peptide inhibits cellular iron efflux by binding to the iron export channel ferroportin and inducing its internalization and degradation. Either hepcidin deficiency or alterations in its target, ferroportin, would be expected to r...

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Détails bibliographiques
Auteurs principaux: Papanikolaou, George, Tzilianos, Michalis, Christakis, John I., Bogdanos, Dionisios, Tsimirika, Konstantina, MacFarlane, Julie, Goldberg, Y. Paul, Sakellaropoulos, Nikos, Ganz, Tomas, Nemeth, Elizabeta
Format: Artigo
Langue:Inglês
Publié: © 2005 by The American Society of Hematology 2005
Sujets:
Red Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895089/
https://ncbi.nlm.nih.gov/pubmed/15671438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4844
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