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Hepcidin in iron overload disorders
Hepcidin is the principal regulator of iron absorption in humans. The peptide inhibits cellular iron efflux by binding to the iron export channel ferroportin and inducing its internalization and degradation. Either hepcidin deficiency or alterations in its target, ferroportin, would be expected to r...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
© 2005 by The American Society of Hematology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895089/ https://ncbi.nlm.nih.gov/pubmed/15671438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4844 |
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