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Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia
Inherited anemias with ineffective erythropoiesis, such as β-thalassemia, manifest inappropriately low hepcidin production and consequent excessive absorption of dietary iron, leading to iron overload. Erythroferrone (ERFE) is an erythroid regulator of hepcidin synthesis and iron homeostasis. Erfe e...
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| Publié dans: | Blood |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4616236/ https://ncbi.nlm.nih.gov/pubmed/26276665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-658419 |
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