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Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

Inherited anemias with ineffective erythropoiesis, such as β-thalassemia, manifest inappropriately low hepcidin production and consequent excessive absorption of dietary iron, leading to iron overload. Erythroferrone (ERFE) is an erythroid regulator of hepcidin synthesis and iron homeostasis. Erfe e...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Kautz, Léon, Jung, Grace, Du, Xin, Gabayan, Victoria, Chapman, Justin, Nasoff, Marc, Nemeth, Elizabeta, Ganz, Tomas
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616236/
https://ncbi.nlm.nih.gov/pubmed/26276665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-658419
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