Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

The deficiency of hepcidin, the hormone that controls iron absorption and its tissue distribution, is the cause of iron overload in nearly all forms of hereditary hemochromatosis and in untransfused iron-loading anemias. In a recent study, we reported the development of minihepcidins, small drug-lik...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ramos, Emilio, Ruchala, Piotr, Goodnough, Julia B., Kautz, Léon, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2012
Gaiak:
Red Cells, Iron, and Erythropoiesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488893/
https://ncbi.nlm.nih.gov/pubmed/22990014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440743
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