Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

The deficiency of hepcidin, the hormone that controls iron absorption and its tissue distribution, is the cause of iron overload in nearly all forms of hereditary hemochromatosis and in untransfused iron-loading anemias. In a recent study, we reported the development of minihepcidins, small drug-lik...

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Detaylı Bibliyografya
Asıl Yazarlar: Ramos, Emilio, Ruchala, Piotr, Goodnough, Julia B., Kautz, Léon, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Red Cells, Iron, and Erythropoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488893/
https://ncbi.nlm.nih.gov/pubmed/22990014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440743
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