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Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

The deficiency of hepcidin, the hormone that controls iron absorption and its tissue distribution, is the cause of iron overload in nearly all forms of hereditary hemochromatosis and in untransfused iron-loading anemias. In a recent study, we reported the development of minihepcidins, small drug-lik...

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Bibliografische gegevens
Hoofdauteurs: Ramos, Emilio, Ruchala, Piotr, Goodnough, Julia B., Kautz, Léon, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488893/
https://ncbi.nlm.nih.gov/pubmed/22990014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440743
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