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Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

The deficiency of hepcidin, the hormone that controls iron absorption and its tissue distribution, is the cause of iron overload in nearly all forms of hereditary hemochromatosis and in untransfused iron-loading anemias. In a recent study, we reported the development of minihepcidins, small drug-lik...

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Detalhes bibliográficos
Main Authors: Ramos, Emilio, Ruchala, Piotr, Goodnough, Julia B., Kautz, Léon, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488893/
https://ncbi.nlm.nih.gov/pubmed/22990014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440743
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