Á lódáil...
The molecular basis of hepcidin-resistant hereditary hemochromatosis
The interaction between the hormone hepcidin and the iron exporter ferroportin (Fpn) regulates plasma iron concentrations. Hepcidin binds to Fpn and induces its internalization and degradation, resulting in decreased iron efflux from cells into plasma. Fpn mutations in N144, Y64N, and C326 residue c...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society of Hematology
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714214/ https://ncbi.nlm.nih.gov/pubmed/19383972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-146134 |
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