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Maternal hepcidin determines embryo iron homeostasis in mice

Iron disorders are associated with adverse pregnancy outcomes, yet iron homeostatic mechanisms during pregnancy are poorly understood. In humans and rodents, the iron-regulatory hormone hepcidin is profoundly decreased in pregnant mothers, which is thought to ensure adequate iron availability for tr...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Sangkhae, Veena, Fisher, Allison L., Chua, Kristine J., Ruchala, Piotr, Ganz, Tomas, Nemeth, Elizabeta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645983/
https://ncbi.nlm.nih.gov/pubmed/32584957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005745
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