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Maternal hepcidin determines embryo iron homeostasis in mice

Iron disorders are associated with adverse pregnancy outcomes, yet iron homeostatic mechanisms during pregnancy are poorly understood. In humans and rodents, the iron-regulatory hormone hepcidin is profoundly decreased in pregnant mothers, which is thought to ensure adequate iron availability for tr...

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Pubblicato in:Blood
Autori principali: Sangkhae, Veena, Fisher, Allison L., Chua, Kristine J., Ruchala, Piotr, Ganz, Tomas, Nemeth, Elizabeta
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645983/
https://ncbi.nlm.nih.gov/pubmed/32584957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005745
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