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Maternal hepcidin determines embryo iron homeostasis in mice

Iron disorders are associated with adverse pregnancy outcomes, yet iron homeostatic mechanisms during pregnancy are poorly understood. In humans and rodents, the iron-regulatory hormone hepcidin is profoundly decreased in pregnant mothers, which is thought to ensure adequate iron availability for tr...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Sangkhae, Veena, Fisher, Allison L., Chua, Kristine J., Ruchala, Piotr, Ganz, Tomas, Nemeth, Elizabeta
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645983/
https://ncbi.nlm.nih.gov/pubmed/32584957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005745
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