Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

The deficiency of hepcidin, the hormone that controls iron absorption and its tissue distribution, is the cause of iron overload in nearly all forms of hereditary hemochromatosis and in untransfused iron-loading anemias. In a recent study, we reported the development of minihepcidins, small drug-lik...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ramos, Emilio, Ruchala, Piotr, Goodnough, Julia B., Kautz, Léon, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2012
Aiheet:
Red Cells, Iron, and Erythropoiesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488893/
https://ncbi.nlm.nih.gov/pubmed/22990014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-440743
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