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Hepcidin in iron overload disorders
Hepcidin is the principal regulator of iron absorption in humans. The peptide inhibits cellular iron efflux by binding to the iron export channel ferroportin and inducing its internalization and degradation. Either hepcidin deficiency or alterations in its target, ferroportin, would be expected to r...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
© 2005 by The American Society of Hematology
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895089/ https://ncbi.nlm.nih.gov/pubmed/15671438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4844 |
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