Hepcidin in iron overload disorders

Hepcidin is the principal regulator of iron absorption in humans. The peptide inhibits cellular iron efflux by binding to the iron export channel ferroportin and inducing its internalization and degradation. Either hepcidin deficiency or alterations in its target, ferroportin, would be expected to r...

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Detalhes bibliográficos
Main Authors: Papanikolaou, George, Tzilianos, Michalis, Christakis, John I., Bogdanos, Dionisios, Tsimirika, Konstantina, MacFarlane, Julie, Goldberg, Y. Paul, Sakellaropoulos, Nikos, Ganz, Tomas, Nemeth, Elizabeta
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Red Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895089/
https://ncbi.nlm.nih.gov/pubmed/15671438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4844
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