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The Hepcidin-Ferroportin System as a Therapeutic Target in Anemias and Iron Overload Disorders
The review summarizes the current understanding of the role of hepcidin and ferroportin in normal iron homeostasis and its disorders. It further discusses the various approaches to therapeutic targeting of hepcidin and ferroportin in iron overload diseases (mainly hereditary hemochromatosis and β-th...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034574/ https://ncbi.nlm.nih.gov/pubmed/22160086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2011.1.538 |
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