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The Hepcidin-Ferroportin System as a Therapeutic Target in Anemias and Iron Overload Disorders
The review summarizes the current understanding of the role of hepcidin and ferroportin in normal iron homeostasis and its disorders. It further discusses the various approaches to therapeutic targeting of hepcidin and ferroportin in iron overload diseases (mainly hereditary hemochromatosis and β-th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034574/ https://ncbi.nlm.nih.gov/pubmed/22160086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2011.1.538 |
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