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The Hepcidin-Ferroportin System as a Therapeutic Target in Anemias and Iron Overload Disorders

The review summarizes the current understanding of the role of hepcidin and ferroportin in normal iron homeostasis and its disorders. It further discusses the various approaches to therapeutic targeting of hepcidin and ferroportin in iron overload diseases (mainly hereditary hemochromatosis and β-th...

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Hlavní autoři: Ganz, Tomas, Nemeth, Elizabeta
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034574/
https://ncbi.nlm.nih.gov/pubmed/22160086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2011.1.538
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