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The Hepcidin-Ferroportin System as a Therapeutic Target in Anemias and Iron Overload Disorders

The review summarizes the current understanding of the role of hepcidin and ferroportin in normal iron homeostasis and its disorders. It further discusses the various approaches to therapeutic targeting of hepcidin and ferroportin in iron overload diseases (mainly hereditary hemochromatosis and β-th...

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Main Authors: Ganz, Tomas, Nemeth, Elizabeta
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034574/
https://ncbi.nlm.nih.gov/pubmed/22160086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2011.1.538
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