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Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading
Hereditary hemochromatosis (HH), an iron overload disease associated with mutations in the HFE gene, is characterized by increased intestinal iron absorption and consequent deposition of excess iron, primarily in the liver. Patients with HH and Hfe-deficient (Hfe(−/−)) mice manifest inappropriate ex...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891009/ https://ncbi.nlm.nih.gov/pubmed/15914561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0629 |
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