A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis

BACKGROUND: Inadequate hepcidin production leads to iron overload in nearly all types of hemochromatosis. We explored the acute response of hepcidin to iron challenge in 25 patients with HFE-hemochromatosis, in two with TFR2-hemochromatosis and in 13 controls. Sixteen patients (10 C282Y/C282Y homozy...

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Autori principali: Girelli, Domenico, Trombini, Paola, Busti, Fabiana, Campostrini, Natascia, Sandri, Marco, Pelucchi, Sara, Westerman, Mark, Ganz, Tomas, Nemeth, Elizabeta, Piperno, Alberto, Camaschella, Clara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069225/
https://ncbi.nlm.nih.gov/pubmed/21173098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.033449
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