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Is the Iron Donor Lipocalin 2 Implicated in the Pathophysiology of Hereditary Hemochromatosis?

Under normal conditions, iron is taken up by the cells through the transferrin-mediated pathway. However, in hereditary hemochromatosis, a common iron-overloading disorder associated with mutations in the HFE gene, iron in plasma exceeds transferrin-binding capacity, and non–transferrin-bound iron (...

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Main Authors: Huang, Hua, Akira, Shizuo, Santos, Manuela M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891005/
https://ncbi.nlm.nih.gov/pubmed/19152427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22699
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