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The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system

INTRODUCTION: Since its discovery, the hemochromatosis protein HFE has been primarily defined by its role in iron metabolism and homeostasis, and its involvement in the genetic disease termed hereditary hemochromatosis (HH). While HH patients are typically afflicted by dysregulated iron levels, many...

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Publicado en:Immun Inflamm Dis
Autores principales: Reuben, Alexandre, Chung, Jacqueline W., Lapointe, Réjean, Santos, Manuela M.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569368/
https://ncbi.nlm.nih.gov/pubmed/28474781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.158
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