Concurrent cisplatin and radiotherapy in advanced head and neck cancer

Tekijä Asif, Rehan, Chandra, Kamlesh, Chopra, Vanita, Bhatt, M. L. B.
Julkaistu 2003

Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington’s Disease

Tekijä Narayanan, K. Lakshmi, Chopra, Vanita, Rosas, H. Diana, Malarick, Keith, Hersch, Steven
Julkaisussa Mol Neurobiol (2015)

LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington’s Disease

Tekijä Chopra, Vanita, Quinti, Luisa, Khanna, Prarthana, Paganetti, Paolo, Kuhn, Rainer, Young, Anne B., Kazantsev, Aleksey G., Hersch, Steven
Julkaisussa J Huntingtons Dis (2016)

A novel method for detecting 7-methyl guanine reveals aberrant methylation levels in Huntington disease

Tekijä Thomas, Beena, Matson, Samantha, Chopra, Vanita, Sun, Liping, Sharma, Swati, Hersch, Steven, Rosas, H. Diana, Scherzer, Clemens, Ferrante, Robert, Matson, Wayne
Julkaistu 2013

A small-molecule therapeutic lead for Huntington's disease: Preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse

Tekijä Chopra, Vanita, Fox, Jonathan H., Lieberman, Greg, Dorsey, Kathryn, Matson, Wayne, Waldmeier, Peter, Housman, David E., Kazantsev, Aleksey, Young, Anne B., Hersch, Steven
Julkaistu 2007

Optogenetic Restoration of Disrupted Slow Oscillations Halts Amyloid Deposition and Restores Calcium Homeostasis in an Animal Model of Alzheimer’s Disease

Tekijä Kastanenka, Ksenia V., Hou, Steven S., Shakerdge, Naomi, Logan, Robert, Feng, Danielle, Wegmann, Susanne, Chopra, Vanita, Hawkes, Jonathan M., Chen, Xiqun, Bacskai, Brian J.
Julkaisussa PLoS One (2017)

Mechanisms of Copper Ion Mediated Huntington's Disease Progression

Tekijä Fox, Jonathan H., Kama, Jibrin A., Lieberman, Gregory, Chopra, Raman, Dorsey, Kate, Chopra, Vanita, Volitakis, Irene, Cherny, Robert A., Bush, Ashley I., Hersch, Steven
Julkaistu 2007

The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

Tekijä Maxwell, Michele M., Tomkinson, Elizabeth M., Nobles, Johnathan, Wizeman, John W., Amore, Allison M., Quinti, Luisa, Chopra, Vanita, Hersch, Steven M., Kazantsev, Aleksey G.
Julkaistu 2011

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of...

Tekijä Frentzel Stefan, Hoyer Daniel, Betschart Claudia, Bleckmann Dorothee, Kama Jibrin A, Dorsey Kate, Chopra Vanita, Connor Teal, Fox Jonathan H, DiFiglia Marian, Paganetti Paolo, Hersch Steven M
Julkaistu 2010-06-01

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of...

Tekijä Fox, Jonathan H, Connor, Teal, Chopra, Vanita, Dorsey, Kate, Kama, Jibrin A, Bleckmann, Dorothee, Betschart, Claudia, Hoyer, Daniel, Frentzel, Stefan, DiFiglia, Marian, Paganetti, Paolo, Hersch, Steven M
Julkaistu 2010

Evaluation of Histone Deacetylases as Drug Targets in Huntington’s Disease models: Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients...

Tekijä Quinti, Luisa, Chopra, Vanita, Rotili, Dante, Valente, Sergio, Amore, Allison, Franci, Gianluigi, Meade, Sarah, Valenza, Marta, Altucci, Lucia, Maxwell, Michele M., Cattaneo, Elena, Hersch, Steven, Mai, Antonello, Kazantsev, Aleksey
Julkaistu 2010

Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse

Tekijä Hu, Yi, Chopra, Vanita, Chopra, Raman, Locascio, Joseph J., Liao, Zhixiang, Ding, Hongliu, Zheng, Bin, Matson, Wayne R., Ferrante, Robert J., Rosas, H. Diana, Hersch, Steven M., Scherzer, Clemens R.
Julkaistu 2011

The Sirtuin 2 Inhibitor AK-7 is Neuroprotective in Huntington Disease Mouse Models

Tekijä Chopra, Vanita, Quinti, Luisa, Kim, Jinho, Vollor, Lorraine, Kumaraswamy, Lakshminarayanan, Edgerly, Christina, Cipicchio, Patricia M., Lauver, Molly A., Choi, Soo Hyuk, Silverman, Richard B., Ferrante, Robert J., Hersch, Steven, Kazantsev, Aleksey G.
Julkaistu 2012

Intestinal alkaline phosphatase targets the gut barrier to prevent aging

Tekijä Kühn, Florian, Adiliaghdam, Fatemeh, Cavallaro, Paul M., Hamarneh, Sulaiman R., Tsurumi, Amy, Hoda, Raza S., Munoz, Alexander R., Dhole, Yashoda, Ramirez, Juan M., Liu, Enyu, Vasan, Robin, Liu, Yang, Samarbafzadeh, Ehsan, Nunez, Rocio A., Farber, Matthew Z., Chopra, Vanita, Malo, Madhu S., Rahme, Laurence G., Hodin, Richard A.
Julkaisussa JCI Insight (2020)

Vitamin D deficiency exacerbates UV/endorphin and opioid addiction

Tekijä Kemény, Lajos V., Robinson, Kathleen C., Hermann, Andrea L., Walker, Deena M., Regan, Susan, Yew, Yik Weng, Lai, Yi Chun, Theodosakis, Nicholas, Rivera, Phillip D., Ding, Weihua, Yang, Liuyue, Beyer, Tobias, Loh, Yong-Hwee E., Lo, Jennifer A., van der Sande, Anita A. J., Sarnie, William, Kotler, David, Hsiao, Jennifer J., Su, Mack Y., Kato, Shinichiro, Kotler, Joseph, Bilbo, Staci D., Chopra, Vanita, Salomon, Matthew P., Shen, Shiqian, Hoon, Dave S. B., Asgari, Maryam M., Wakeman, Sarah E., Nestler, Eric J., Fisher, David E.
Julkaisussa Sci Adv (2021)

KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

Tekijä Quinti, Luisa, Dayalan Naidu, Sharadha, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R., Vodicka, Petr, Van Kanegan, Michael J., Kaltenbach, Linda S., Crawford, Lisa A., Fuszard, Matthew, Higgins, Maureen, Miller, James R. C., Farmer, Ruth E., Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M., Ellerby, Lisa M., Weerapana, Eranthie, Schwarzschild, Michael A., Steegborn, Clemens, Leavitt, Blair R., Degterev, Alexei, Tabrizi, Sarah J., Lo, Donald C., DiFiglia, Marian, Thompson, Leslie M., Dinkova-Kostova, Albena T., Kazantsev, Aleksey G.
Julkaisussa Proc Natl Acad Sci U S A (2017)