Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington’s Disease T Lymphocytes

door Miller, James R. C., Träger, Ulrike, Andre, Ralph, Tabrizi, Sarah J.
Gepubliceerd in PLoS One (2015)

Short-term anesthesia inhibits formalin-induced extracellular signal-regulated kinase (ERK) activation in the rostral anterior cingulate cortex but not in the spinal cord

door Tochiki, Keri K, Maiarù, Maria, Miller, James R C, Hunt, Stephen P, Géranton, Sandrine M
Gepubliceerd in Mol Pain (2015)

RNA-Seq of Huntington’s disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation

door Miller, James R. C., Lo, Kitty K., Andre, Ralph, Hensman Moss, Davina J., Träger, Ulrike, Stone, Timothy C., Jones, Lesley, Holmans, Peter, Plagnol, Vincent, Tabrizi, Sarah J.
Gepubliceerd in Hum Mol Genet (2016)

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients

door Wild, Edward J., Boggio, Roberto, Langbehn, Douglas, Robertson, Nicola, Haider, Salman, Miller, James R.C., Zetterberg, Henrik, Leavitt, Blair R., Kuhn, Rainer, Tabrizi, Sarah J., Macdonald, Douglas, Weiss, Andreas
Gepubliceerd in J Clin Invest (2015)

Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells

door Miller, James R. C., Pfister, Edith L., Liu, Wanzhao, Andre, Ralph, Träger, Ulrike, Kennington, Lori A., Lo, Kimberly, Dijkstra, Sipke, Macdonald, Douglas, Ostroff, Gary, Aronin, Neil, Tabrizi, Sarah J.
Gepubliceerd in Sci Rep (2017)

Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models

door Träger, Ulrike, Andre, Ralph, Magnusson-Lind, Anna, Miller, James R.C., Connolly, Colúm, Weiss, Andreas, Grueninger, Stephan, Silajdžić, Edina, Smith, Donna L., Leavitt, Blair R., Bates, Gillian P., Björkqvist, Maria, Tabrizi, Sarah J.
Gepubliceerd in Neurobiol Dis (2015)

Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease

door Hensman Moss, Davina J., Flower, Michael D., Lo, Kitty K., Miller, James R. C., van Ommen, Gert-Jan B., ’t Hoen, Peter A. C., Stone, Timothy C., Guinee, Amelia, Langbehn, Douglas R., Jones, Lesley, Plagnol, Vincent, van Roon-Mom, Willeke M. C., Holmans, Peter, Tabrizi, Sarah J.
Gepubliceerd in Sci Rep (2017)

KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

door Quinti, Luisa, Dayalan Naidu, Sharadha, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R., Vodicka, Petr, Van Kanegan, Michael J., Kaltenbach, Linda S., Crawford, Lisa A., Fuszard, Matthew, Higgins, Maureen, Miller, James R. C., Farmer, Ruth E., Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M., Ellerby, Lisa M., Weerapana, Eranthie, Schwarzschild, Michael A., Steegborn, Clemens, Leavitt, Blair R., Degterev, Alexei, Tabrizi, Sarah J., Lo, Donald C., DiFiglia, Marian, Thompson, Leslie M., Dinkova-Kostova, Albena T., Kazantsev, Aleksey G.
Gepubliceerd in Proc Natl Acad Sci U S A (2017)