Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington’s Disease T Lymphocytes

Por Miller, James R. C., Träger, Ulrike, Andre, Ralph, Tabrizi, Sarah J.
Publicado no PLoS One (2015)

JAK/STAT Signalling in Huntington’s Disease Immune Cells

Por Träger, Ulrike, Magnusson, Anna, Lahiri Swales, Nayana, Wild, Edward, North, Janet, Lowdell, Mark, Björkqvist, Maria
Publicado em 2013

Laquinimod dampens hyperactive cytokine production in Huntington's disease patient myeloid cells

Por Dobson, Lucianne, Träger, Ulrike, Farmer, Ruth, Hayardeny, Liat, Loupe, Pippa, Hayden, Michael R., Tabrizi, Sarah J.
Publicado no J Neurochem (2016)

The Immune Response to Melanoma Is Limited by Thymic Selection of Self-Antigens

Por Träger, Ulrike, Sierro, Sophie, Djordjevic, Gordana, Bouzo, Basma, Khandwala, Shivani, Meloni, Antonella, Mortensen, Monika, Simon, Anna Katharina
Publicado em 2012

RNA-Seq of Huntington’s disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation

Por Miller, James R. C., Lo, Kitty K., Andre, Ralph, Hensman Moss, Davina J., Träger, Ulrike, Stone, Timothy C., Jones, Lesley, Holmans, Peter, Plagnol, Vincent, Tabrizi, Sarah J.
Publicado no Hum Mol Genet (2016)

Mutant huntingtin impairs immune cell migration in Huntington disease

Por Kwan, Wanda, Träger, Ulrike, Davalos, Dimitrios, Chou, Austin, Bouchard, Jill, Andre, Ralph, Miller, Aaron, Weiss, Andreas, Giorgini, Flaviano, Cheah, Christine, Möller, Thomas, Stella, Nephi, Akassoglou, Katerina, Tabrizi, Sarah J., Muchowski, Paul J.
Publicado em 2012

Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models

Por Träger, Ulrike, Andre, Ralph, Magnusson-Lind, Anna, Miller, James R.C., Connolly, Colúm, Weiss, Andreas, Grueninger, Stephan, Silajdžić, Edina, Smith, Donna L., Leavitt, Blair R., Bates, Gillian P., Björkqvist, Maria, Tabrizi, Sarah J.
Publicado no Neurobiol Dis (2015)

Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression

Por Weiss, Andreas, Träger, Ulrike, Wild, Edward J., Grueninger, Stephan, Farmer, Ruth, Landles, Christian, Scahill, Rachael I., Lahiri, Nayana, Haider, Salman, Macdonald, Douglas, Frost, Chris, Bates, Gillian P., Bilbe, Graeme, Kuhn, Rainer, Andre, Ralph, Tabrizi, Sarah J.
Publicado em 2012

HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation

Por Träger, Ulrike, Andre, Ralph, Lahiri, Nayana, Magnusson-Lind, Anna, Weiss, Andreas, Grueninger, Stephan, McKinnon, Chris, Sirinathsinghji, Eva, Kahlon, Shira, Pfister, Edith L., Moser, Roger, Hummerich, Holger, Antoniou, Michael, Bates, Gillian P., Luthi-Carter, Ruth, Lowdell, Mark W., Björkqvist, Maria, Ostroff, Gary R., Aronin, Neil, Tabrizi, Sarah J.
Publicado em 2014