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Laquinimod dampens hyperactive cytokine production in Huntington's disease patient myeloid cells

Huntington's disease (HD) is a neurodegenerative condition characterized by pathology in the brain and peripheral tissues. Hyperactivity of the innate immune system, due in part to NFκB pathway dysregulation, is an early and active component of HD. Evidence suggests targeting immune disruption...

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Podrobná bibliografie
Vydáno v:J Neurochem
Hlavní autoři: Dobson, Lucianne, Träger, Ulrike, Farmer, Ruth, Hayardeny, Liat, Loupe, Pippa, Hayden, Michael R., Tabrizi, Sarah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982105/
https://ncbi.nlm.nih.gov/pubmed/26823290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13553
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