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Laquinimod dampens hyperactive cytokine production in Huntington's disease patient myeloid cells
Huntington's disease (HD) is a neurodegenerative condition characterized by pathology in the brain and peripheral tissues. Hyperactivity of the innate immune system, due in part to NFκB pathway dysregulation, is an early and active component of HD. Evidence suggests targeting immune disruption...
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| Pubblicato in: | J Neurochem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4982105/ https://ncbi.nlm.nih.gov/pubmed/26823290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13553 |
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