A flexible polyglutamine hinge opens new doors for understanding huntingtin function

gan Giorgini, Flaviano
Cyhoeddwyd 2013

Is modulating translation a therapeutic option for Huntington’s disease?

gan Giorgini, Flaviano
Cyhoeddwyd 2011

DJ-1 in Parkinson’s Disease: Clinical Insights and Therapeutic Perspectives

gan Repici, Mariaelena, Giorgini, Flaviano
Cyhoeddwyd yn J Clin Med (2019)

Connecting the dots in Huntington's disease with protein interaction networks

gan Giorgini, Flaviano, Muchowski, Paul J
Cyhoeddwyd 2005

Rab11 as a modulator of synaptic transmission

gan Giorgini, Flaviano, Steinert, Joern R
Cyhoeddwyd 2013

Modeling Huntington disease in yeast: Perspectives and future directions

gan Mason, Robert P, Giorgini, Flaviano
Cyhoeddwyd 2011

Aggregation-Prone Proteins Modulate Huntingtin Inclusion Body Formation in Yeast

gan Kantcheva, Ralitsa B., Mason, Robert, Giorgini, Flaviano
Cyhoeddwyd 2014

MSY2 and MSY4 Bind a Conserved Sequence in the 3′ Untranslated Region of Protamine 1 mRNA In Vitro and In Vivo

gan Giorgini, Flaviano, Davies, Holly G., Braun, Robert E.
Cyhoeddwyd 2001

Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition?

gan Collier, Mary EW, Zhang, Shaowei, Scrutton, Nigel S, Giorgini, Flaviano
Cyhoeddwyd yn Drug Discov Today (2021)

A network of protein interactions determines polyglutamine toxicity

gan Duennwald, Martin L., Jagadish, Smitha, Giorgini, Flaviano, Muchowski, Paul J., Lindquist, Susan
Cyhoeddwyd 2006

Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

gan Spiers, Jereme G., Breda, Carlo, Robinson, Sue, Giorgini, Flaviano, Steinert, Joern R.
Cyhoeddwyd yn Front Mol Neurosci (2019)

Ablation of kynurenine 3-monooxygenase rescues plasma inflammatory cytokine levels in the R6/2 mouse model of Huntington’s disease

gan Bondulich, Marie Katrin, Fan, Yilan, Song, Yeojin, Giorgini, Flaviano, Bates, Gillian P.
Cyhoeddwyd yn Sci Rep (2021)

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington's disease

gan Giorgini, Flaviano, Guidetti, Paolo, Nguyen, QuangVu, Bennett, Simone C., Muchowski, Paul J.
Cyhoeddwyd 2005

A Novel Sit4 Phosphatase Complex Is Involved in the Response to Ceramide Stress in Yeast

gan Woodacre, Alexandra, Lone, Museer A., Jablonowski, Daniel, Schneiter, Roger, Giorgini, Flaviano, Schaffrath, Raffael
Cyhoeddwyd 2013

Advantages of brain penetrating inhibitors of kynurenine-3-monooxygenase for treatment of neurodegenerative diseases

gan Zhang, Shaowei, Collier, Mary E.W., Heyes, Derren J., Giorgini, Flaviano, Scrutton, Nigel S.
Cyhoeddwyd yn Arch Biochem Biophys (2020)

Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease

gan Steinert, Joern R., Campesan, Susanna, Richards, Paul, Kyriacou, Charalambos P., Forsythe, Ian D., Giorgini, Flaviano
Cyhoeddwyd 2012

Parkinson’s disease-associated mutations in DJ-1 modulate its dimerization in living cells

gan Repici, Mariaelena, Straatman, Kornelis R., Balduccio, Nadia, Enguita, Francisco J., Outeiro, Tiago F., Giorgini, Flaviano
Cyhoeddwyd 2012

β-Defensin Genomic Copy Number Does Not Influence the Age of Onset in Huntington’s Disease

gan Vittori, Angelica, Orth, Michael, Roos, Raymund A. C., Outeiro, Tiago F., Giorgini, Flaviano, Hollox, Edward J.
Cyhoeddwyd 2013

Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase

gan Miller-Fleming, Leonor, Antas, Pedro, Pais, Teresa Faria, Smalley, Joshua L., Giorgini, Flaviano, Outeiro, Tiago Fleming
Cyhoeddwyd 2014

RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies

gan Koss, David J., Bondarevaite, Odeta, Adams, Sara, Leite, Marta, Giorgini, Flaviano, Attems, Johannes, Outeiro, Tiago F.
Cyhoeddwyd yn Brain Pathol (2020)